HOME WEI ZHANG GROUP RESEARCH PUBLICATIONS SEMINARS Lab & Equip NEWS

GROUP NEWS
  • Our research group involved in the organization of International Symposia on Fluorous Technologies (ISoFT2017) and made one oral and 4 poster presentations (Aug. 2017)
  • A joint paper with Prof. Jian Zhu's lab at Univ. of Rochester Medical School "A Novel Bromodomain Inhibitor Reverses HIV-1 Latency Through Specific Binding with BRD4 to Promote Tat and P-TEFb Association" is accepted by Front. Microbiol. (May 2017)
  • Shuai Liu presented a poster "A Novel Bromodomain and Extra-terminal Domain Inhibitors (BETi) That Reverses HIV-1 Latency" at the 7th Annual Research Retreat of UMass Center for Clinical and Translational Science (May 2017)
  • Congratulations Alex Muthengi for receiveing a travel grant from ACS Green Chemistry Institute Pharmaceutical Roundtable to attend and present at the 21th Annual Green Chemistry & Green Engineering Conference. June 13-15 in Reston, Virginia (Apr. 2017)
  • Undergraduate students Marc Legris & Francesca Corsini presented posters at the Annual Massachusetts Statewide Undergraduate Research Conference at UMass Amherst (Apr. 2017)
  • Undergraduate student Francesca Corsini's popster "Structural Relationship Study on BI2536 to Synthesize a Dual Kinase Bromodomain Inhibitor" won second place for Undergraduate presentation in the Environmental Colloquium. Congratulations! (Apr. 2017)
  • A joint paper (with Prof. W. Yi) "Metal-free Difluoromethylthiolation, Trifluoromethylthiolation, and Perfluoroalkylthiolation with HCF2SO2Na, CF3SO2Na or RfSO2Na" is published in Adv. Synth. Catal. as a cover article (Apr. 2017)
  • A joint paper (with Dr. Xin Huang) "Recyclable Organocatalysts for the One-pot Asymmetric Synthesis of 2-Fluorocyclohexanols Bearing Six Contiguous Stereocenters" is published in Adv. Synth. Catal. (Apr. 2017)
  • Welcome Dr. Belete A. Legesse joining our lab as a visiting scholar. Dr. Legesse recetly received his PhD from Northeastern University (Apr. 2017)
  • Welcome Dr. Leo Zhu joining our lab as a visiting scholar. Dr. Zhu has many years of medicinal chemistry experince working in US pharmacutical industry (Mar. 2017)
  • Welcome Prof. Wensheng Zhang from Jiaozuo Teacher's College joining our lab as a visiting scholar. Dr. Zhang is supported by the State Scholarship Fund of China (Mar. 2017)
  • A joint paper (with Prof. J.-P. Zou) "Metal-free Radical C-H Methylation of Pyrimidinones and Pyridinones with Dicumyl Peroxide" is published in Green Chem. (Jan. 2017)
  • A joint paper (with Prof. J. Bradner) "Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET" is published in ChemMedChem (Nov. 2016)
  • During a trip to China, Prof. Zhang gave three invited talks at Changzhou University, Changzhou Institute of Engineering and Technology, and Shanghai Institute of Technology (Nov. 2016)
  • Our group members participated the UMB/Yale Green Chemistry Workshop. In additional to 5 posters from our lab, Shuai Liu and Prof. Zhang gave oral presentations (Sep. 2016)
  • Prof. Zhang is invited to give a keynote talk at 6th IUPAC Conference on Green Chemistry in Venice, Italy (Sep. 2016)
  • Shuai Liu received 2016 SAPA-Biopeptek Graduate Travel Grant (Sep. 2016)
  • Welcome Lvqi Jiang from Nanjing University of Science and Technology joining our lab as a visiting PhD student. Lvqi is supported by the State Scholarship Fund of China (Sep. 2016)
  • Shuai Liu, Miao Liu and Marc Legris from our lab attended the a 3-day Green Chemistry Workshop at Yale University. Prof. Zhang gave a keynote talk (Aug. 31 - Sept. 2, 2016)
  • Welcome Prof. Gagan Dhawan from University of Delhi joining our lab as a visiting scholar. Dr. Dhawan received Raman Fellowship funded by UGC, India (Aug. 2016)
  • Welcome Bruno Moukette joining our lab as a Fulbright Scholar. Bruno is a PhD student from University of Yaounde I, Cameroon (Aug. 2016)
  • Prof. Zhang was invited to give a plenary talk at Drug Discovery & Therapy World Congress 2016 in Boston (Aug. 2016)
  • Prof. Zhang gave an invited talk in Advances in Green Chemistry Symposia at the ACS meeting in Philadephia (Aug. 2016)
  • Prof. Zhang was invited to visit South Korea and gave talks at Chung-Ang University and Seoul National University (Aug. 2016)
  • Prof. Zhang is appointed as a Section Editorial Board for 'Green Chemistry' for the journal Molecules
  • During his visit in China, Prof. Zhang gave invited talks at Xaanxi Normal University and Shanghai University (Jul. 2016)/a>
  • Prof. Zhang gave two talks at 2016 ACS Middle Atlantic Regional Meeting, Riverdale, NY (Jun. 2016)
  • A joint paper (with Prof. Wenbin Yi) "2,2-Difluoro-1,3-diketones as gem-Difluoroenolate Precusors for Asymmetric Aldol Addition with N-Benzyl Isatins" is acceprted by Adv. Synth. Catal. Congratulations to Xin and other co-authors (Jun. 2016)
  • Jinyan Li and Marc Legr received Genzyme Undergraduate Research Fellowship for Fall 2016 semester (Jun. 2016)
  • Shaui Liu received a travel grant to attend the 2016 American Chemical Society Summer School on Green Chemistry & Sustainable Energy at the Colorado School of Mines (Jun. 2016)
  • Our paper "Organocatalytic One-pot Asymmetric Synthesis of Thiolated Spiro-lactam-oxindoles Bearing Three Stereogenic Centers" is accepted by J. Org. Chem. Congratulations to Xin and other co-authors (Jun. 2016)
  • Alex Muthengi received a travel grant to attend the University at Buffalo Chemistry Graduate Student Symposium (May 2016)
  • Shuai Liu received a travel grant to attend the symposium "Innovations in Chemistry towards Sustainable Urban Living" in Univ. of Toronto (May 2016)
  • A joint paper (with N. Gray and S. Treon's labs at Dana-Farber Cancer Institute) "HCK Is a Survival Determinant Transactivated by Mutated MYD88, and A Direct Target of Ibrutinib" is accepted for publication in Blood (May 2016)
  • Welcome undergraduate student Marc Legris joining our lab (Apr. 2016)
  • Shaui Liu received the PhD Dissertation Grant from the University (Apr. 2016)
  • Dr. Hailemichael Yosief gave a talk "New Small Molecule Bromodomain Inhibitors" and Chisom Udengwu gave a poster at New England Regional SACNAS Conference in Boston (Apr. 2016)
  • Xin Huang successfully defended his PhD thesis "Organocatalysis for Michael Addition-based Transformations Involving Fluorination and Other Asymmetric Reactions". He will be a faculty member at Zhejiang Normal University, congratulations! (Apr. 2016)
  • Kenny Pham successfully defended his master thesis "Synthesis of Fluorinated Compounds by One-Pot Reactions and Asymmetric Organocatalysis" (Mar. 2016)
  • Our paper "A Pot-economy and Diastereoselective Synthesis Involving Catalyst-free Click Reaction for Fused-triazolobenzodiazepines" is accepted for publication in Green Chemistry. Congratulations to Xiaofeng and other co-authors (Mar. 2016)
  • Welcome undergraduate student Jinyan Li joining our lab (Feb. 2016)
  • Xin Huang received the PhD Dissertation Grant from the University (Jan. 2016)
  • Francesca Corsini and Chisom Udengwu are selected as Sanofi Genzyme & Oracle Undergraduate Research Fellowships for the semester of spring 2016 (Jan. 2016)
  • Prof. Zhang serves as a Co-Chair of the symposium "New Green Techniques for Medicinal Chemistry" at the PacifiChem, Hawaii (Dec. 2015)
  • Invited by the School of Green Chemistry and Engineering at the University of Toledo, Prof. Zhang delivered a seminar "Fluorous Green Synthesis for Medicinal Chemistry and Organocatalysis" (Nov. 2015)
  • Welcome graduate student Nathalie Myrthil and undergraduate student Rebeca Cortazio joining our lab (Oct. 2015)
  • A joint paper "Direct Trifluoromethylthiolation and Perfluoroalkylthiolation of SP2 C-H Bonds with NaSO2CF3 or NaSO2Rf" is published in Angew. Chem. Int. Ed. 2015, 45, 14965-14969 (Oct. 2015)
  • Francesca Corsini is selected as a Sanofi Genzyme & Oracle Undergraduate Research Fellowship for the semester of fall 2015 (Sep. 2015)
  • At the 21st ISFC&ISoFT'15 Conference in Como, Italy, Prof. Zhang received International Fluorous Technologies Award (Aug. 2015)
  • Prof. Zhang co-chaired the 3rd Annual Workshop of the Global Green Chemistry Centres (G2C2) Network. Our research group members are involved in the hosting of the event at UMass Boston on Aug. 20-21, 2015
  • Xiaofeng Zhang receive the Best Poster Award at the 3rd Annual Workshop of the Global Green Chemistry Centres (G2C2) Network (Aug. 2015)
  • At the 250th ACS National Meeting in Boston, graduate student Xin Huang delivered an oral presentation on organocatalysis, and Shuai Liu presented a poster on the discovery of bromidomian inhitertors (Aug. 2015)
  • Prof. Zhang was invited by the editor of C&EN News to make commentary on 2015 Presidential Green Chemistry Challenge Awards (C&EN News, Aug. 24, 2105, p32-35)
  • A review article "Recent Advances in Sulfur- and Phosphorous-centered Radical Reactions for the Formation of S-C and P-C Bonds" is published as a Tetrahedron Report in Tetrahedron 2015, 71, 7481-7529 (June 2015)
  • Prof. Zhang was invited to deliver an opening plenary lecture at 5th International Conference for Young Chemists in Penang, Malaysia. The theme of this conference is Green Chemistry towards a Sustainable Tomorrow (Aug. 2015)
  • Prof. Zhang was invited to joing the editorial board of Green Syntheses (Jul. 2015)
  • Prof. Zhang serves on the International Advisory Board of Drug Discovery & Therapy World Congress, Boston (Jul. 2015)
  • Welcome summer intern students Uriel Tayvah (Princeton University) and Filipe Echart de Oliveira (Federal University of Rio Grande, Brazil) joining our lab (June 2015)
  • Graduate students Xin Huang and Shuai Liu, and undergraduate students Jeremy Hyatt, Francesca Corsini, and Joshua Aguirre Carrion receive NIH U54 grant internships for summer 2015 (June 2015)
  • Shuai Liu receive the travel scholarship to attend 2015 Green Chemistry Symposium organized by Green Chemistry Initiative at the University of Toronto (May 2015)
  • Xin Huang receive the travel grant to attend Graduate Student Symposium at the University at Buffalo (May 2015)
  • Welcome Cecilia Clamens from Rennes Chemistry and Chemical Engineering School (France) joining our group as a summer intern (Apr. 2015)
  • See UMass Boston "Outstanding Faculty" profile of Prof. Zhang (Apr. 2015)
  • As part of a series of Earth Day events organized by the Office for Sustainability at Harvard University, Prof. Zhang is invited to give a talk in the Chemistry and Chemical Biology Department of Harvard on April 16th, 2015. See an article about his talk.
  • Undergraduate student Udengwu joining University of Massachusetts Medical School Summer Enrichment Program (Apr. 2015)
  • Undergraduate students Anthony P. Tran and Jeremy H. Hyatt present two posters at the 21st Annual Massachusetts Statewide Undergraduate Research Conference (Apr. 2015)
  • Graduate students Xin Huang and Shuai Liu present two posters at 2015 Northeastern Student Chemistry Research Conference and Career Symposium (Apr. 2015)
  • Welcome undergraduate student Francesca Corsini joining our group (Mar. 2015)
  • Prof. Zhang is invited to deliver the opening Plenary Lecture at the 13th IBN SINA International Conference on Pure and Applied Heterocyclic Chemistry, Hurghada, Egypt (Feb. 2015)
  • Welcome Prof. Wenbin Yi from Nanjing University of Science and Technology joining our group as a visiting scholar (Feb. 2015)
  • A joint patent application "Inhibitors of transcription factors and users thereof" WO2015013635A2 with Prof. James Bradner's lab at Harvard Medical School is published (Jan. 2015)
  • We have completed the moving of our research lab to the new Integrated Sciences Complex, the room #s are ISC-3560 and 3570 (Jan. 2015)
  • Welcome Jinlong Qia from Nanjing University of Science and Technology joining our group as a visiting PhD student (Jan. 2015)
  • ChisomUdengwu is selected as a McNair Fellow
  • Graduate students Shuai Liu and Xin Huang, and undergraduate student Jeremy Hyatt receive NIH U54 grant internships for winter 2014 and spring 2015 (Dec. 2014)
  • Welcome Miao Liu joining our group as a lab technician (Dec. 2014)
  • Shiva Dastjerdi is selected as a UMass Boston representative to attend and make a poster presentation at the Annual Biomedical Research Conference for Minority Students (ABRCMS) in San Antonio (Nov. 2014)
  • Jeremy H. Hyatt and Anthony P. Tran are selected as recipients of the Sanofi Genzyme Undergraduate Research Fellowship for academic year 2014-2015 (Nov. 2014)
  • Prof. Zhang serves as a session Chair and delivered talks at BIT's 5th Annual International Congress of Medichem, Suzhou, China (Nov. 2014)
  • Welcome Alex M. Muthengi joining our group as a new PhD student (Nov. 2014)
  • A joint paper "Biased Multicomponent Reactions to Develop Novel Bromodomain Inhibitors" with Prof. James Bradner's lab at Harvard Medical School is published in J. Med. Chem. 2014, 57, 9019-9027.
  • Welcome Raymond Borg and Paul Huttunen joining our group as new PhD students (Sep. 2014)
  • Welcome Dr. Hailemichael Yosief from University of Cincinnati joining our group as an NIH-sponsored postdoc (Sep. 2014)
  • Welcome Prof. Wei Wang from Shaanxi Normal University joining our group as a visiting scholar (Sep. 2014)
  • Graduate students Xin Huang and Shuai Liu, and undergraduate student Jeremy Hyatt for receiving NIH U54 grant internships for fall 2014 (Sep. 2014)
  • Anthony P. Tran is selected as a Fellow of UMass Boston Research Scholars Academy for Undergraduates (Aug. 2014)
  • Xin Huang, Shuai Liu, Yuan Xia, and Shiva Dastjerdi present posters at UMass Boston Summer Research Symposium (Aug. 2014)
  • Shuai Liu is the recipient of $5,000 graduate scholarship designated by Dr. John C. Warner as part of his 2014 SCI Perkin Medal Award (Aug. 2014)
  • Prof. Zhang was invited to give a talk at the 2nd Annual Symposium and Workshop of the Global Green Chemistry Centres. Cape Town, South Africa (Aug. 2014)
  • Prof. Zhang was appointed as a guest professor of Shanghai Institute of Technology (Jul. 2014)
  • During his spring and summer trips to Asia, Prof. Zhang is invited to give seminars at Shanghai Institute of Technology, Jinan University (Guangzhou), Shanghai Institute of Materia Medica, Jiangxi Science and Technology Normal University, Taiwan Tunghai University, and Taiwan National Chiao Tung University (Mar. to Jul., 2014)
  • Prof. Zhang was invited to give a talk at ASC Sustainability Forum - A Supply Chain Discussion of Trends and Market Drivers in Baltimore, MD (Jul. 2014)
  • Caitlin Pollock together with her team members Yuan Xia and Shiva Dastjerdi publish the 1st issue of UMass Boston Green Chemistry Newsletter (Jul. 2014)
  • Xin Huang is selected as an NSF Scholar for attending the 18th Annual Green Chemistry & Green Engineering Conference in North Bethesda, MD (Jun. 2014)
  • Prof. Zhang serves as a session Chair of the BIT's 3rd Annual Congress and EXPO of Advanced Materials-2014, Chongqing, China (Jun. 2014)
  • A joint paper "Fluorescent Visualization of Src Using BODIPY-Dasatinib" with Profs. Nathanael Gray and Priscilla Yang's labs at Dana-Farber Cancer Institute and Harvard Medical School is published in ChemBioChem 2014, 15, 1317-1324
  • Shuai Liu represents the research group to present a poster at the 5th Annual UMCCTS Research Retreat, UMass Medical School (May 2014)
  • Prof. Zhang was invited to give a talk at a green chemistry workshop at University of Toronto (May 2014)
  • Congratulate Xin Huang for reciving the Mastricola Award from the department for his outstanding graduate research
  • Congratulate Corey Pasakarnis, Fjorela Dhroso, and Yuan Xia for receiving Honors in Chemistry Award from the department
  • Xin Huang, Shuai Liu, Yuan Xia and Shiva Dastjerdi receive U54 summer internships to work on NIH-supported research at UMass Boston and Dana-Farber Cancer Institute (May 2104)
  • Undergraduate students Corey Pasakarnis, Yuan Xia, Shiva Dastjerdi, Fjorela Dhroso, and Dan T. Nguyen presented posters at The 20th Annual Massachusetts Statewide Undergraduate Research Conference at UMass Amherst (Apr. 25, 2014)
  • Undergraduate students Corey Pasakarnis, Yuan Xia, Shiva Dastjerdi, and Fjorela Dhroso presented posters at The 16th Annual Northeast Student Chemistry Research Conference at Boston University. Shiva received "The Graduate Women in Science Award" (Apr. 12, 2014)
  • Our research proposal "Green Organocatalysis for Asymmetric Synthesis of Biologically Interesting Fluorinated Compounds" received 2014 Joseph P. Healey Grant (Apr. 2014)
  • Prof. Zhang is appointed as a Co-Editor-in-Chief of the newly launched journal Current Green Chemistry
  • Our review article "Synthesis and Uses of Fluorous and Highly Fluorinated Macrocyclic and Spherical Molecules" (J. Fluorine Chem., 2014, 157, 84-105is one of the most downloaded articles of the jounal (Mar. 14, 2014)
  • Asha Kadam defended her PhD thesis "Green Techniques to Improve Grignard Reactions and Synthesize Heterocyclic Molecules" (Mar. 4, 2014)
  • Four group members, Corey Pasakarnis, Yuan Xia, Dan T. Nguyen, and Fjorela Dhroso, receive 2014 UMB Undergraduate Research funds (Jan. 2014)
  • Dan T. Nguyen is selected as a Fellow of UMass Boston Research Scholars Academy for Undergraduates (Jan. 2014)
  • Asha Kadam and Prof. Zhang are invited as the panelists to participate the GC3 Green Chemistry Innovation Webinar "Advancing Green Chemistry Innovation in the Pharmaceutical Industry: The GCI Pharmaceutical Roundtable's Research Grant Program" presented by Julie Manley (Dec. 12, 2013)
  • See an article in UMass Boston News "UMass Boston's Center for Green Chemistry Leads Charge for Environmental Awareness in Science" (Nov. 13, 2103)
  • Welcome Xiaofeng Zhang joining our group as a lab technician (Oct. 2013)
  • Welcome visiting Professor Qiangqao Chen from Nanjing University of Science and Technology joining our group (Oct. 2013)
  • Welcome following undergraduate students joining our group: Dan T. Nguyen, Shiva Dastjerdi, Fjorela Dhroso, Shayna Zanker, and Anthony P. Tran (Oct. 2013)
  • See UMass Boston "Outstanding Faculty" profile of Prof. Zhang (Sep. 2013)
  • Welcome visiting Professor Sanjun Zhi from Huaiyin Normal University joining our group (Sep. 2013)
  • Welcome new graduate students Kenny Pham and Caitlin Coelho joining our group (Sep. 2013)
  • Prof. Zhang is appointed as a member of the Center and Institutes Committee for the School for the Enviroment (Aug. 2013)
  • Our and Prof. James Bradner's labs at the Harvard Medical School received a joint NIH U54 grant for a full project "Development of Small-Molecule Bromodomain Inhibitors for Cancer Therapy" (Aug. 2013)
  • A research article on the Grignard reaction published in Green Chemistry (2013, 15, 1880-1888) is selected as a "Hot Paper"
  • A joint paper (with Stephen J. Elledge's group at the Harvard Medical School) "Protein interaction discovery using parallel analysis of translated ORFs (PLato)" is published in Nature Biotechnology 2013, 31,331-334