Dr. Marianna Torok
Assistant Professor, Chemistry

Education:
Postdoctoral Research, Massachusetts Institute of Technology, Cambridge, MA
Postdoctoral Research, University of Southern California, Los Angeles, CA
Ph.D., University of Szeged, Faculty of Medicine, Szeged, Hungary
B.S/MS., University of Szeged, Faculty of Science, Szeged, Hungary

Current Position:
Assistant Professor, Chemistry
Office: S-1-128
Research Laboratory: S-1-117
Telephone: 287-6199
Email: marianna.torok@umb.edu

Current/Recently Taught Courses:
CH130 Lab 2 - Physiological Chemistry (Spring 2008)
BIOCHM384 - Biochemistry Lecture II (Spring 2008)
CH253 Disc 3 and Lab 4 - Organic Chemistry (Fall 2007)
BIOCHM383 - Biochemistry Lecture I (Fall 2007)

Research Interests:
Physical Biochemistry, Medicinal Chemistry, Protein Structure and Dynamics, Biological Applications of Electron Paramagnetic Resonance Spectroscopy,
Protein Misfolding and Amyloidogenesis, Alzheimer's Disease, Amyloid-beta Peptide.


Research Group:
Cyndie Metellus (Undergraduate Research Student)
ZiJuan Zhang (M.S. Student)
Abha Sood (Ph.D. Student)


Publications:

  1. Mhadgut SC, Török M , Dasgupta S, Török B. Nature of Proline-Induced Enantiodifferentiation in Asymmetric Pd Catalyzed Hydrogenations: Is the Catalyst Really Indifferent? Catal.Lett., in press, 2008.
  2. Török M , Abid M, Mhadgut SC, Török B. Organofluorine Inhibitors of Amyloid Fibrillogenesis. Biochemistry 45: 5377-5383, 2006.
  3. Mhadgut SC, Török M , Esquibel J, Török B. Highly Asymmetric Heterogeneous Catalytic Hydrogenation of Isophorone on Proline Modified Base-Supported Palladium Catalysts. Journal of Catalysis 238: 441-448, 2006 .
  4. Török B, Abid M, London G, Esquibel J, Török M, Mhadgut SC, Yan P, Prakash GKS. Highly Enantioselective Organocatalytic Hydroxyalkylation of Indoles with ethyl trifluoropyruvate. Angew. Chem. Int. Ed. 44: 3086-3089, 2005.
  5. Mhadgut SC, Bucsi I, Török M, Török B. Sonochemical asymmetric hydrogenation of isophorone on proline modified Pd/Al2O3 catalysts. Chemical Communications 984-985, 2004.
  6. Jayasinghe S, Török M, Langen R. Interaction of Islet Amyloid Polypeptide with Phospholipid Vesicles. Biophysical Journal 84: 58A-58A Part 2 Suppl. S, 2003.
  7. Török M, Milton S, Kayed R, Wu P, McIntire T, Glabe CG, Langen R. Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labeling. The Journal of Biological Chemistry 277: 40810-5, 2002.
  8. Török B, Balázsik K, Török M, Felföldi K, Bartók M. Enantiodifferentiation in Cinchona-Modified Platinum-Catalyzed Sonochemical Hydrogenations. Catalysis Letters 81: 55-62, 2002.
  9. Török M, Ritzel R, Butler PC, Langen R. Structure and Dynamics of Human Islet Amyloid Polypeptide (Amylin) Studied by Site-directed Spin Labeling. Diabetes 50(Suppl.): A361-A361, 2001.
  10. Török B, Török M, Rózsa-Tarjáni M, Pálinkó I, Horváth LI, Kiricsi I, Molnár A. Interactions between solvent molecules and the reduced forms of silico-molybdic acid studied by ESR and NMR spectroscopies and molecular modelling. Inorganica Chimica Acta 298: 77-83, 2000.
  11. Török B, Balázsik K, Török, Szöllösi G, Bartók M. Asymmetric sonochemical reactions. Enantioselective hydrogenation of alpha-ketoesters over platinum catalysts. Ultrasonics Sonochemistry 7: 151-5, 2000.
  12. Török M, Hideg K, Dux L, Horváth LI. Accessibility of protein sulfhydril groups to nitroxyl spin labels. Journal of Molecular Structure 408/409: 177-180, 1997.
  13. Horváth LI, Török M, Hideg K, Dux L. Dynamic aspects of the incorporation of proteins into biological membranes. Journal of Molecular Recognition 10: 188-93, 1997.
  14. Ferdinándy P, Csont T, Csonka C, Török M, Dux M, Németh J, Horváth LI, Dux L, Szilvássy Z, Jancsó G. Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP? Naunyn-Schmiedeberg's Archives of Pharmacology 356: 356-63, 1997.
  15. Török M, Jakab G, Bérczi A, Dux L, Horváth LI. Rotational mobility of Ca2+ATPase of sarcoplasmic reticulum in viscous media. Biochimica et Biophysica Acta 1326: 193-200, 1997.
  16. Olah GA, Prakash GKS, Török B, Török M. Effect of Acid/Hydrocarbon Ratio, Temperature and Contact Time on the Isobutane-Isobutylene Alkylation Catalyzed by Trifluoromethanesulfonic Acid. Catalysis Letters 40: 137-142, 1996.
  17. Olah GA, Török B, Shamma T, Török M, Prakash GKS. Solid Acid (Superacid) Catalyzed Adamantylation of Substituted Benzenes. Catalysis Letters 42: 5-13, 1996.
  18. Török M, Jakab G, Bérczi A, Dux L, Horváth LI. Hydrodynamic Mobility of Ca2+ATPase of sarcoplasmic reticulum in viscous solvents. Progress in Biophysics & Molecular Biology 65(suppl. 1): p. 46, P-A3-26, 1996.
  19. Török B, Török M, Bartók M. Temperature and Hydrogen Pressure Dependence in the Ring Opening of Methylcyclobutane over Pt/SiO2 catalyst. Catalysis Letters 33: 321-330, 1995.

Back to the Main Chemistry Page